When introduced into the bloodstream haemocirculation drug distributed in the system, practically does not penetrate beyond the vascular bed, does not accumulate in the tissues and organs. It does not cross the intact blood-brain barrier. The drug does not penetrate the red blood cells. When administered intravenously, the drug its relation to plasma proteins is 10%. During the 3 hours after administration there is a relatively rapid decline in concentration by 30 minutes, then a gradual decrease to the nandrolone phenylpropionate. Filters in the kidneys and excreted in the urine in unchanged form. During the first 30 minutes after administration of the urine output of about 15% of drug administered, and during the first 3 watches – more than 50%. Patients with impaired renal function of the drug in a small amount can be eliminated by the liver. Since breast milk output in minimum quantities.
Indications for use.
Angiography, digital subtraction angiography, computed tomography, angiocardiography, ascending pyelography, lymphography, urethrocystography, splenoportography, fistulography, arthrography, hysterosalpingography, preoperative cholangiography.
Angiography, digital subtraction angiography, computed tomography (including .ch. abdominal computed tomography in combination with barium sulphate), excretory urography, hysterosalpingography.
Decompensated congestive heart failure; severe hypertension; for ascending pyelography – acute uroinfektsiya; for venography – acute phlebitis; plasmacytoma; severe hypertension; acute coronary insufficiency; active tuberculosis; shock; collapse; hypercoagulation; chronic renal failure; hyperthyroidism; nodular goiter; pronounced cerebral atherosclerosis; liver failure; general heavy state; pregnancy;lactation; children’s age.
Hysterosalpingography not carried out in the presence of acute inflammatory processes in the pelvic area. Endoscopic retrograde cholangiopancreatography is not carried out in acute pancreatitis.
Contraindicated use nandrolone phenylpropionatefor myelography, ventriculography and cisternography (possible neurotoxic effect).
Hypersensitivity (including to iodine-containing radiopaque drugs).
Be wary appoint studies using in patients with decompensated diabetes mellitus, pulmonary emphysema, pheochromocytoma, subclinical hyperthyroidism, generalized myeloma; patients with severe cardiovascular disease, and pulmonary hypertension; patients with a history of allergies (asthma, allergodermatoses, hay fever, drug and food allergies).
Dosage and administration.
Apply the product only under medical supervision.
Dial into the syringe contrast agent must be immediately prior to the survey.
The solution is a contrast agent is designed for single use only. For the prevention of thrombus formation, during angiography, it is often necessary to wash the intravenous catheter physiological sodium chloride solution. Before using the drug should be warmed to body temperature. Introduction of the solution is carried out in the position of the patient “lying.”
For intracavitary administration (in the bladder, renal pelvis) nandrolone phenylpropionate must be diluted with isotonic sodium chloride solution or 5% glucose solution to give a 30% solution. Angiography. Preparing the patient for angiography: the night appointed anxiolytic, in the evening and in the morning – a cleansing enema; on the day of the study the patient should not eat. Administered intraarterially to angiokardiografii, aortography, arteriography, selective angiography. Venography and splenoportography conducted by intravenous administration. Phlebography: lower limb administered 20-40 mL of the upper – 10-20 mL of 60% solution triombrasta ® at a rate of 3-5 ml / sec. When vena cava study drug is administered in an amount of 25-30 ml at a rate of 10-13 ml / sec. Pictures are made already during the injection. After inspection is necessary to ensure elimination of the contrast agents of the extremities: the limb is lifted, and the vein is washed 50-70 ml of 0.9% sodium chloride solution. The peripheral arteriography: use 20 ml of the lower limbs and upper – 10-20 ml of 60% solution. For a better tolerability recommended administration to the direction of blood flow against. Cerebral Angiography: on average 7 ml of a 60% solution is administered into the carotid artery or introduced into 4 ml of the vertebral artery. When both seriography in 2 planes, nandrolone phenylpropionate is enough, otherwise the second projection is necessary to repeat the injection.