Increased severity of side effects. Treatment – symptomatic. No data on the effect of hemodialysis or peritoneal dialysis, the concentration of sumatriptan in plasma.
sumatriptan should be used only if the npp diagnosis of migraine is no doubt that when it should be used as soon as possible after the onset of a migraine attack, although it is equally effective when used at any stage of attack. Can not be used as a preventive measure.
As with other protivomigrenoznyh funds, the appointment of sumatriptan in patients with previously diagnosed with migraine or patients with atypical migraine is necessary to exclude other potentially serious neurological conditions. It should be noted that patients with migraine are at increased risk of certain cerebrovascular events (stroke or transient ischemic attack).
Sumatriptan should not be administered to patients with suspected heart disease without prior examination in order to avoid cardiovascular disease. Such patients include postmenopausal women, men over the age of 40 years and patients with risk factors for coronary heart disease. Although the survey has not always possible to detect heart disease in some patients, in very rare cases, they develop side effects to the cardiovascular system. After receiving sumatriptan may experience transient intense pain and tightness in the chest, extending to the neck. If there is reason to believe that these symptoms are a manifestation of coronary heart disease, it is necessary to conduct appropriate diagnostic testing.
Patients with migraine may occur drowsiness, npp associated, with both the disease itself and the reception of sumatriptan, so they need to be especially careful while driving and working with moving machinery.
There was no interaction with sumatriptan propranolol, flyunarizinom, pizotifenom and ethyl alcohol.
When concomitantly with ergotamine celebrated long vasospasm. Sumatriptan may be administered no earlier than 24 hours after administration of preparations containing ergotamine; Conversely, drugs containing ergotamine, you can assign no sooner than 6 hours after administration of sumatriptan.
Perhaps the interaction between sumatriptan inhibitors as well as sumatriptan and drugs from the group of selective inhibitors of serotonin reuptake . There are some reports about the weakness of the development, hyperreflexia and poor coordination in patients after administration of sumatriptan and drugs from the SSRI. In the case of co-administration of sumatriptan and npp should be closely monitored condition of the patient.