Trypsin has a pronounced anti-inflammatory and anti-edema properties, is able to break down dead tissue sections, fibrinous education, viscous secrets and exudates. Relative to healthy tissue enzyme activity and is safe due to the presence of trypsin inhibitors (specific and nonspecific). It phenylpropionate does not affect the hemostatic system.
bronchiectasis, lung abscess, pleural effusion, postoperative atelectasis, empyema; treatment of purulent wounds and burns; chronic suppurative otitis, purulent sinusitis, sinusitis; acute thrombophlebitis, acute and chronic odontogenic osteomyelitis, inflammatory and degenerative forms of periodontal disease, acute iridium iridocyclitis, bleeding in the chamber of the eye, and swelling of the periorbital tissue after injuries and operations, obstruction slezootvodyaschyh ways.
Hypersensitivity, heart failure, pulmonary emphysema with respiratory failure, decompensated form of lung tuberculosis, liver dystrophy and cirrhosis, infectious hepatitis, kidney damage, pancreatitis, hemorrhagic diathesis.
Dosage and method of use of
crystalline trypsin applied intramuscularly phenylpropionate intraplevralno, in the form of aerosols and electrophoresis. Intramuscular: trypsin adults a day for children 0.0025 g 1 time per day. Diluted for injection immediately before use 0.005 g of crystalline trypsin in 2.1 ml 0.9% sodium chloride solution or 0.5-2% solution of procaine.
The course of treatment 6-15 injections. Applied also with trypsin electrophoresis: one procedure 10 mg of trypsin (dissolved in 15-20 mL distilled water) are administered with the negative pole. Inhalation: at 0.005-0.01 g in 2.3 ml of 0.9% sodium chloride solution through inhaler or via a bronchoscope. After inhalation, rinse your mouth with warm water and wash the nose. Eye drops: 0.2-0.25% solution which was prepared immediately before use, 3-4 times a day for 1-3 days.Intraplevralno: 1 time per day 10- 20 mg dissolved in 20-50 ml of 0.9% sodium chloride, after administration is desirable frequent changes in body position; on day 2 after installation release usually liquefied exudate. Local: in the form of powder or solution, to dry or necrotic wounds superimposed packs. Three-layered woven webs of dialdegidtsellyulozy soaked in trypsin, is applied to the wound (after processing) and fasten the bandage to the wound left no more than 24 hours. Before use, the web is moistened with distilled water or a solution Frc. Complete phenylpropionate wound cleansing time of necrotic tissue and pus – 24-72 hours if necessary -. Re-apply.
Allergic reactions. Fever, tachycardia. Soreness and redness at the injection site after intramuscular administration. Inhalation of trypsin can occur irritation of the mucous membranes of the upper respiratory tract and hoarseness.